Xiaodong Wang Selected Research

Nausea

10/2019	Population Pharmacokinetics of Rolapitant in Patients With Chemotherapy-Induced Nausea and Vomiting.
3/2019	Effects of rolapitant administered orally on the pharmacokinetics of dextromethorphan (CYP2D6), tolbutamide (CYP2C9), omeprazole (CYP2C19), efavirenz (CYP2B6), and repaglinide (CYP2C8) in healthy subjects.
1/2019	An Open-Label, Randomized, Pivotal Bioequivalence Study of Oral Rolapitant.
1/2019	Pharmacokinetics, Safety, and Tolerability of Rolapitant Administered Intravenously Following Single Ascending and Multiple Ascending Doses in Healthy Subjects.
1/2019	Pharmacokinetic Interactions of Rolapitant With Cytochrome P450 3A Substrates in Healthy Subjects.
1/2019	Absorption, metabolism, and excretion of the antiemetic rolapitant, a selective neurokinin-1 receptor antagonist, in healthy male subjects.
8/2018	Effects of Rolapitant Administered Intravenously on the Pharmacokinetics of a Modified Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan) in Healthy Subjects.
1/2018	Effects of Rolapitant Administered Intravenously or Orally on the Pharmacokinetics of Digoxin (P-glycoprotein Substrate) and Sulfasalazine (Breast Cancer Resistance Protein Substrate) in Healthy Volunteers.
1/2018	Pharmacokinetics of Rolapitant in Patients With Mild to Moderate Hepatic Impairment.
12/2017	Bioequivalence of Intravenous and Oral Rolapitant: Results From a Randomized, Open-Label Pivotal Study.

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Xiaodong Wang Research Topics

Disease

195	Neoplasms (Cancer) 04/2024 - 01/2003
35	Infections 03/2024 - 07/2003
32	Inflammation (Inflammations) 02/2024 - 09/2012
26	Neoplasm Metastasis (Metastasis) 08/2023 - 01/2002
24	Breast Neoplasms (Breast Cancer) 12/2022 - 03/2004
22	Hepatocellular Carcinoma (Hepatoma) 02/2024 - 01/2014
20	Colorectal Neoplasms (Colorectal Cancer) 10/2023 - 01/2013
18	Prostatic Neoplasms (Prostate Cancer) 03/2021 - 01/2002
16	Necrosis 01/2023 - 08/2005
15	Fibrosis (Cirrhosis) 02/2024 - 10/2013
15	Carcinogenesis 01/2024 - 03/2006
14	Leukemia 09/2023 - 05/2002
14	Hemorrhage 01/2023 - 04/2007
13	Glioma (Gliomas) 03/2024 - 06/2011
13	Pain (Aches) 10/2023 - 08/2011
13	Stomach Neoplasms (Stomach Cancer) 07/2023 - 02/2016
12	Lung Neoplasms (Lung Cancer) 01/2023 - 12/2011
11	Colonic Neoplasms (Colon Cancer) 01/2024 - 09/2015
11	Systemic Lupus Erythematosus (Libman-Sacks Disease) 06/2023 - 01/2018
10	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2024 - 11/2007
10	Hypoxia (Hypoxemia) 10/2023 - 01/2013
10	Vomiting 10/2019 - 12/2017
10	Nausea 10/2019 - 12/2017
9	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/2023 - 02/2012
9	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 09/2023 - 08/2014
9	Melanoma (Melanoma, Malignant) 01/2022 - 05/2013
8	Fatty Liver 02/2024 - 05/2008
8	Rheumatoid Arthritis 10/2023 - 01/2019
8	Liver Cirrhosis (Hepatic Cirrhosis) 01/2023 - 03/2002
8	Traumatic Brain Injuries (Traumatic Brain Injury) 11/2021 - 09/2013
7	Rectal Neoplasms (Rectal Cancer) 10/2023 - 03/2010
7	Chronic Hepatitis B 08/2023 - 01/2014
7	Wounds and Injuries (Trauma) 06/2023 - 04/2003
7	Thyroid Neoplasms (Thyroid Cancer) 04/2023 - 06/2012
7	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2021 - 12/2016
7	Spinal Cord Injuries (Spinal Cord Injury) 10/2016 - 10/2011
6	Dermatomyositis (Dermatopolymyositis) 01/2024 - 04/2020
6	COVID-19 01/2024 - 01/2022
6	Fever (Fevers) 12/2023 - 06/2015
6	Cicatrix (Scar) 05/2023 - 02/2012
6	HIV Infections (HIV Infection) 01/2023 - 09/2011
6	Liver Neoplasms (Liver Cancer) 01/2023 - 08/2011
6	Type 2 Diabetes Mellitus (MODY) 10/2022 - 07/2013
6	Disease Progression 01/2022 - 09/2012
6	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 07/2013
6	Cerebral Palsy (Spastic Diplegia) 01/2019 - 05/2012
5	Pancreatic Neoplasms (Pancreatic Cancer) 06/2024 - 01/2011
5	Neuroinflammatory Diseases 02/2024 - 12/2021

Drug/Important Bio-Agent (IBA)

68	Proteins (Proteins, Gene)FDA Link 06/2024 - 01/2002
28	Biomarkers (Surrogate Marker)IBA 03/2024 - 12/2012
27	c-Mer Tyrosine KinaseIBA 03/2024 - 05/2013
25	Phosphotransferases (Kinase)IBA 04/2024 - 06/2009
21	CytokinesIBA 03/2024 - 06/2009
19	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 07/2009
17	MicroRNAs (MicroRNA)IBA 08/2023 - 08/2014
15	Long Noncoding RNAIBA 12/2023 - 03/2016
15	Small Interfering RNA (siRNA)IBA 01/2023 - 06/2009
13	RNA (Ribonucleic Acid)IBA 04/2024 - 02/2014
11	Therapeutic UsesIBA 01/2024 - 03/2017
11	rolapitantIBA 10/2019 - 12/2017
10	LigandsIBA 01/2022 - 05/2013
10	Neurokinin-1 Receptor AntagonistsIBA 10/2019 - 12/2017
10	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 01/2015 - 08/2005
9	VaccinesIBA 12/2022 - 01/2018
9	EnzymesIBA 10/2022 - 03/2006
9	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 02/2022 - 05/2013
9	Ethanol (Ethyl Alcohol)IBA 01/2022 - 04/2007
8	Tyrosine Kinase InhibitorsIBA 02/2020 - 05/2013
7	Oxaliplatin (Eloxatin)FDA LinkGeneric 03/2024 - 01/2017
7	Fluorescent Dyes (Fluorescent Probes)IBA 02/2024 - 04/2019
7	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 09/2023 - 03/2015
7	Antiviral Agents (Antivirals)IBA 01/2023 - 02/2014
6	Hormones (Hormone)IBA 04/2024 - 07/2015
6	AntibodiesIBA 01/2024 - 02/2013
6	IronIBA 12/2023 - 10/2019
6	AlbuminsIBA 08/2023 - 04/2014
6	Interleukin-6 (Interleukin 6)IBA 04/2023 - 01/2019
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2023 - 03/2013
6	Fluorouracil (Carac)FDA LinkGeneric 03/2023 - 12/2016
6	MRX-2843IBA 01/2023 - 03/2016
6	Alanine Transaminase (SGPT)IBA 01/2023 - 11/2011
6	Messenger RNA (mRNA)IBA 01/2023 - 02/2016
6	DNA (Deoxyribonucleic Acid)IBA 12/2022 - 07/2003
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2022 - 09/2004
6	Metformin (Glucophage)FDA LinkGeneric 10/2022 - 01/2016
6	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 12/2011
6	Estrogens (Estrogen)FDA Link 01/2022 - 03/2004
6	AntiemeticsIBA 01/2022 - 01/2018
6	UNC2025IBA 01/2021 - 09/2015
5	Oncogene Proteins (Oncogene Protein)IBA 04/2024 - 01/2003

Therapy/Procedure

88	Therapeutics 02/2024 - 09/2004
54	Drug Therapy (Chemotherapy) 03/2024 - 12/2011
15	Transplantation 01/2021 - 05/2012
13	Immunotherapy 01/2024 - 06/2014
8	Cesarean Section (Caesarean Section) 02/2024 - 04/2014
8	Radiotherapy 01/2024 - 07/2013
7	Liver Transplantation 12/2023 - 06/2021
6	Lasers (Laser) 12/2021 - 08/2011
6	Castration 01/2019 - 12/2015
5	Neoadjuvant Therapy 02/2024 - 01/2014